Purified Anti-Human CD59 Antibody[P282 (H19)] (AN011260P)
| Alternate Names | CD 59, CD_antigen=CD59, CD59 antigen complement regulatory protein, CD59 antigen p18 20, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, CD59 molecule, CD59 molecule complement regulatory protein, Cd59a, Complement regulatory protein, EL32 and G344), Human leukocyte antigen MIC11, Ly 6, Ly 6 like protein, Lymphocytic antigen CD59/MEM43, MAC inhibitory protein, MAC IP, MAC-inhibitory protein, MACIP, MEM43 antigen, Membrane attack complex (MAC) inhibition factor, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MGC2354, p18 20, Surface antigen recognized by monoclonal 16.3A5, T cell activating protein, MEM, MIC, MSK, p18, 16.3A, MIC11MSK, HRF, MIN, CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, 1F5 antigen, 20 kDa homologous restriction factor, CD59 antigen, CD59 glycoprotein, FLJ38134, FLJ92039, HRF 20, Ly 6, MIC11MSK21, Protectin, H19, 1F-5Ag |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD59 is a 19-25 kD glycosylphosphatidylinositol (GPI)-anchored glycoprotein also known as protectin, MACIF, and H19. It is broadly expressed on hematopoietic and non-hematopoietic cells. CD59 inhibits the cytolytic activity of complement by binding to C9, inhibiting incorporation into C5b-8, and preventing the terminal steps in complement polymerization of the membrane attack complex. CD59 has also been reported to play a role in T cell activation. |
| Immunogen | Recombinant Human CD59 protein |
| Abbre | CD59 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | Purified Mouse IgG2a, κ Isotype Control[C1.18.4], Functional Grade |
| Applications |
FCM
|
| Research Areas | Stem Cells;Signal Transduction;Cardiovascular Biology;Immunology;CDs;Receptor Tyrosine kinases;Intracellular Kinases;Hematopoietic Stem Cell Markers |
| Cellular Localization |
Cell membrane, Secreted
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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