Purified Anti-Human CD66c Antibody[DA019] (AN015620P)
| Alternate Names | Carcinoembryonic antigen related cell adhesion molecule 6, Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen), Carcinoembryonic antigen-related cell adhesion molecule 6, CD 66c, CD66c antigen, CEA LIKE PROTEIN, CEACAM 6, CEAM6, MGC93832, Non specific cross reacting antigen, Non-specific crossreacting antigen, Normal cross reacting antigen, Normal cross-reacting antigen, CEACAM, CEACAM6, CD66c, CEAL, NCA |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood Granulocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. |
| Immunogen | Recombinant Human CD66c protein |
| Abbre | CD66C |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | Purified Mouse IgG2a, κ Isotype Control[C1.18.4], Functional Grade |
| Applications |
FCM
|
| Research Areas | CDs;Immunology;Cancer;Tags & Cell Markers;Tumor Biomarkers |
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Expressed in neutrophils. Expressed in columnar epithelial and goblet cells of the colon. Expressed in numerous tumor cell lines.
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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