Purified Anti-Human CD96 Antibody[NK92.39] (E-AB-F1447A)
| Alternate Names | Cell surface antigen CD, TACTILE, Cell surface antigen CD96, T cell-activated increased late expression protein, T-cell surface protein tactile, CD96 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Molt-4 |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD96, known as TACTILE (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expressed on NK cells, T cells (up-regulated upon activation), and some acute myeloid leukemia (AML) cells, but not on normal B and myeloid cells. A soluble form of CD96 has been found in serum. CD96 is involved in T- and NK-cell adhesion through interaction with its ligand, CD155 (polio virus receptor). |
| Immunogen | Recombinant Human CD96 protein |
| Abbre | CD96 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM
|
| Research Areas | CDs;Stem Cells;Immunology;Tumor Biomarkers;Cancer Stem Cell Markers;Hematopoietic Stem Cell Markers |
| Cellular Localization |
Membrane
|
| Tissue Specificity |
Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells.
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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