Purified Anti-Human Foxp3 Antibody[259D] (AN014200P)
| Alternate Names | FOXP, FOXP3, AIID, DIETER, IPEX, JM2, PIDX, XPID, Scurfin |
| Clone | |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human Foxp3 gene |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen | Recombinant Human FOXP3 protein |
| Abbre | FOXP3 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM
|
| Research Areas | Pyroptosis;Epigenetics and Nuclear Signaling;Cell Biology;Immunology |
| Cellular Localization |
Nucleus, Cytoplasm
|
| Tissue Specificity |
Down-regulated in regulatory T-cells (Treg) during inflammation, Up-regulated by FOXO3.
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN015440P | Purified Anti-Human FOXP3 Antibody[DA014] | DA014 |
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