Purified Anti-Human IL-4 Antibody[MP4-25D2], Functional Grade (E-AB-F12030)
![Purified Anti-Human IL-4 Antibody[MP4-25D2], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Elab Fluor®700 FITC None (AF/LE) PE PE/Elab Fluor®594 Unconjugated Show More
| Isotype | Rat IgG1, κ |
| Host | Rat |
| Reactivity | Human |
| Applications | FCM, Neut |
| Clonality | Monoclonal |
| Abbre | IL-4 |
| Synonyms | B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor, IL-4, Interleukin-4 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Research Areas | Immunology |
| Clone | MP4-25D2 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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