Purified Anti-Human IL-9 Antibody[MH9A4] (AN007820P)
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For research use only.
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human IL-9 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Mouse IgG2b,κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | ICFCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human IL-9 protein |
| Abbre | IL-9 |
| Synonyms | Cytokine P, Interleukin, TCGF, IL9, HP40, IL-9, P40, Cytokine P40, Interleukin-9, P40 Cytokine, P40 T-cell and Mast Cell Growth Factor, T-cell Growth Factor P40, TCGF3, TCGFIII |
| Swissprot | |
| Cellular Localization | Secreted |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Clone No. | MH9A4 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | IL-9 is a 14 kDa cytokine originally named P40 and identified by its proliferative effects on T cell populations. The receptor, which is a heterodimer of the gamma chain portion of the IL-2 receptor and the IL-9R chain, activates Jak/STAT signaling pathways upon binding its ligand. Since the discovery of IL-9, numerous other functions have been observed. It induces Th17 and Treg differentiation in CD4+ T cells, IgE production in B cells, and the differentiation and proliferation of mast cells. IL-9 expression was initially observed in Th2 cells, but has since been found in Th17, eosinophil, and mast cells. Th9 cells, a newly discovered subset of CD4+ T cells, are characterized by the secretion of large amounts of IL-9 and IL-10. Th9 development is induced by stimulation of undifferentiated CD4+ with IL-4 and TGF beta. Th2 cells can also be driven towards a Th9 phenotype in the presence of TGF beta. |
| Cat.No. | Product Name | Sizes |
|---|---|---|
| AN007830P | Purified Anti-Human IL-9 Antibody[MH9A3] | 100μg , 25μg , 100mg , 50mg , 25mg , 5mg , 1mg |
| AN007840P | Purified Anti-Human IL-9 Antibody[MH9D1] | 100μg , 25μg , 100mg , 50mg , 25mg , 5mg , 1mg |
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