Purified Anti-Human/Monkey CD16 Antibody[3G8], Functional Grade (E-AB-F12360)
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For research use only.
| Alternate Names | FCR, IMD, FCG, Fcgr, IGFR, IgG Fc Receptor III, CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20, FCGR3A, CD16a Antigen, Fc-Gamma RIII, Fc-gamma RIIIa, Fc-Gamma RIII-Alpha, IgG Fc Receptor III-2, Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A, Fc&, gamma-RIIIA-A, CD16a, CD 16, CD 16a, CD16B, CD16b antigen, Fc fragment of IgG, Fc fragment of IgG low affinity IIIa receptor, Fc fragment of IgG low affinity IIIa receptor (CD16), Fc fragment of IgG receptor IIIa, Fc gamma R3, Fc gamma receptor III 2 (CD 16), Fc gamma receptor III A, Fc gamma receptor IIIA, Fc gamma receptor IIIb (CD 16), Fc gamma RIII, Fc gamma RIII alpha, Fc gamma RIII beta, Fc gamma RIIIa, Fc gamma RIIIb, Fc of IgG, FCG 3, FCG3A, Fc-gamma receptor III2 (CD 16), Fc-gamma receptor III2 (CD16), Fc-gamma receptor IIIb (CD16), FCgammaRIIIA, FCGR 3, FCGR 3A, FCGR3A protein, FCGRIII-2, FcR 10, FcR10, IGFR 3, IgG Fc receptor III 1, IgG Fc receptor III 2, immunoglobulin G Fc receptor III, immunoglobulin G Fc receptor III-2, low affinity III, low affinity IIIa, Low affinity IIIa receptor, low affinity IIIb, Low affinity immunoglobulin gamma Fc region receptor III A, Low affinity immunoglobulin gamma Fc region receptor IIIB, neutrophil-specific antigen NA, receptor (CD16), receptor (CD16a), receptor (CD16b), receptor for, receptor for (CD16), FCG, FCR, Fcgr, IgG Fc receptor III, IGFR, FCGR3B, CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb, CD16b and FCGR3B, CD16b and FCGR4B, CD16b and FCGR5B, CD16b and FCGR6B, Fc-gamma RIII-beta, IgG Fc receptor III-1, Low affinity immunoglobulin gamma Fc region receptor III-B, IGFR3, Fc&, gamma-RIIIB-B, CD16A, Fc fragment of IgG receptor IIIb, FCGR3A |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Block Reported in the literaturee;Stim Reported in the literature |
| Background | CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD16 protein |
| Abbre | CD16 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human;Rhesus;Cynomolgus |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM;Block;Stim
|
| Research Areas | Immunology;Stem Cells;Immunology |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Smed-Sörensen A, et al. Blood. 2008 May 1;111(9):5037-5045. Yamin R, et al. Nature. 2021 Nov 18;599(7885):465-470. |
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