Purified Anti-Human/Monkey CD86 Antibody[IT2.2], Functional Grade (E-AB-F12690)
| Alternate Names | Activation B7-2 antigen, Activation B7-2 antigen 3, B-lymphocyte activation antigen B7-2, B-lymphocyte activation antigen B7-2 2, B7 2, B7-2, B7.2, B70, B72 antigen, BU63, CD28 antigen ligand 2, CD28 antigen ligand 2 2, Cd28l2, CD28LG, CD28LG2, CD86, CD86 antigen, CD86 molecule, CLS1, CTLA-4 Counter-Receptor B, CTLA-4 Counter-Receptor B7.2, CTLA-4 counter-receptor B7.2 2, Early T-cell costimulatory molecule, Early T-cell costimulatory molecule 1, ETC, ETC-1, FUN, FUN 1, FUN-1, LAB, LAB72, Ly-58, Ly58, MB7, MB7-2, Membrane glycoprotein, MGC34413, T-lymphocyte activation antigen CD86, TS/A-2 |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human/Monkey peripheral blood monocytes cell |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human/Monkey CD86 protein |
| Abbre | CD86 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human;Monkey |
| Clonality | Monoclonal |
| Purification Method | > 98%, Protein A/G purified, ≥ 95% monomer by analytical SEC |
| Endotoxin | < 1 EU/mg determined by LAL assay |
| Isotype | Mouse IgG2b, κ |
| Isotype Control | Purified Mouse IgG2b, κ Isotype Control[MPC-11], Functional Grade |
| Applications |
FCM
|
| Research Areas | Immunology;Microbiology;Stem Cells;Kits;Lysates;Other |
| Concentration |
≥ 3 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Sterile PBS, pH 7.2. Contains no stabilizers or preservatives |
| Storage | Store at 4℃ valid for 12 months or -20℃ valid for long term storage, avoid freeze/thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.
Searching publications using CD86 as the keyword shows that the gene above is closely associated with CD86 in research. Results are sorted in descending order of research relevance. (The displayed numbers represent the number of publications in which both terms co-occur.)
| Cat.No. | Product Name | Sizes |
|---|---|---|
| E-AB-F098130 | Purified Mouse IgG2b, κ Isotype Control[MPC-11], Functional Grade | 100μg , 100mg , 50mg , 25mg , 5mg , 1mg |
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