Purified Anti-Human/Mouse IL-5 Antibody[TRFK5], Functional Grade (E-AB-F12050)
![Purified Anti-Human/Mouse IL-5 Antibody[TRFK5], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Elab Fluor®700 None (AF/LE) PE Unconjugated Show More
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse IL-5 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Depletion Reported in the literature, Neut Reported in the literature |
| Isotype | Rat IgG1, κ |
| Host | Rat |
| Reactivity | Human, Mouse |
| Applications | ICFCM, Depletion, Neut |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse IL-5 protein |
| Isotype Control | Purified Rat IgG1, κ Isotype Control[HRPN], Functional Grade |
| Abbre | IL-5 |
| Synonyms | B-cell differentiation factor I, IL-5, Interleukin-5, T-cell replacing factor, TRF |
| Swissprot | |
| Cellular Localization | Secreted |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology |
| Clone | TRFK5 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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