Purified Anti-Human p16INK4a Antibody[DA012] (AN011230P)
| Alternate Names | CCM2, CDK4 inhibitor p16 INK4, Cell cycle negative regulator beta, Cyclin dependent kinase 4 inhibitor A, Cyclin Dependent Kinase Inhibitor 2A, Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4), Cyclin dependent kinase inhibitor 2A isoform 4, Cyclin dependent kinase inhibitor 2A isoforms 1/2/3, Cyclin dependent kinase inhibitor p16, Multiple tumor suppressor 1, INK, CMM, CDKN, P16INK, MTS, CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16, Cyclin-dependent kinase inhibitor 2A |
| Clone | |
| Verified Samples | Verified Samples in FCM: Hela cells |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. |
| Immunogen | Recombinant Human p16INK4a protein |
| Abbre | p16INK4a |
| Swissprot | |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rabbit IgG |
| Applications |
FCM
|
| Cellular Localization |
Cytoplasm, Nucleus
|
| Tissue Specificity |
Cyclin-dependent kinase inhibitor 2A Imported, Cyclin-dependent kinase 4 inhibitor A (CDK4I), Multiple tumor suppressor 1 (MTS-1), p16-INK4a (p16-INK4; p16INK4A), CDKN2A, CDKN2, MTS1
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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