Purified Anti-Human TYRP1 Antibody[TA99] (AN007880P)
| Alternate Names | OCA, CAS, b-PROTEIN, CATB, GP75, OCA3, TRP, TRP1, CAS2, TYRP, TYRRP, TYRP1 |
| Clone | |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human TYRP1 gene |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | Tyrosinase-related protein 1, also known as TYRP1 or MEL-5, is an enzyme found in melanocytes and is involved in the synthesis of melanin. TYRP1 stabilizes tyrosinase and modulates its catalytic activity. It is also involved in the maintenance of melanosome structures, as well as the proliferation and cell death of melanocytes. |
| Immunogen | Recombinant Human TYRP1 protein |
| Abbre | TYRP1 |
| Swissprot | |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rabbit IgG, κ |
| Applications |
FCM
|
| Research Areas | Epigenetics and Nuclear Signaling;Cancer;Tags and Cell Markers;Cell Biology;Signal Transduction;Tumor Biomarkers. |
| Cellular Localization |
Melanosome membrane
|
| Tissue Specificity |
Pigment cells.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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