Purified Anti-Mouse CD103 Antibody[M290], Functional Grade (E-AB-F10900)
![Purified Anti-Mouse CD103 Antibody[M290], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Biotin Elab Fluor®488 Elab Fluor®647 None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD103 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Neut Reported in the literature |
| Isotype | Rat IgG1, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM, Neut |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse CD103 protein |
| Abbre | CD103 |
| Synonyms | CD103, Integrin alpha M290, Integrin alpha-E, Itgae |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology |
| Clone | M290 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD103 is the alpha E integrin, which forms a heterodimer with integrin beta 7. The heterodimer complex binds to E-cadherin. It is expressed in on T cells, notably in subpopulations in the lamina propria, on regulatory T cells, or resident memory T cells, and a subset of dendritic cells in gut mucosa. CD103 is thought to be involved with homing to intestinal epithelial sites and has been associated with high levels of TGF-beta presence. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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