Purified Anti-Mouse CD105 Antibody[MJ7/18] (E-AB-F1233A)
For research use only.
| Verified Samples | Verified Samples in FCM: Bend.3 |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD105 protein |
| Abbre | CD105 |
| Synonyms | HHT, ORW1, AI528660, AI662476, CD105, END, Endo, Endoglin, HHT1, ORW, S-endoglin, Edg, Eng, END, HHT1, ORW, ORW1, CD 105, CD105 antigen, EGLN, FLJ41744, Osler Rendu Weber syndrome 1, RP11 228B15.2, SN6 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Clone No. | MJ7/18 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. |
Other Clones
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Other Formats
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APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
FITC
None (AF/LE)
PE
Unconjugated
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