Purified Anti-Mouse CD105 Antibody[MJ7/18], Functional Grade (E-AB-F12330)
![Purified Anti-Mouse CD105 Antibody[MJ7/18], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Elab Fluor®700 FITC None (AF/LE) PE Unconjugated Show More
| Verified Samples | Verified Samples in FCM: Bend.3 |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Activ Reported in the literaturee |
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM, Activ |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD105 protein |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3], Functional Grade |
| Abbre | CD105 |
| Synonyms | HHT, ORW1, AI528660, AI662476, CD105, END, Endo, Endoglin, HHT1, ORW, S-endoglin, Edg, Eng, END, HHT1, ORW, ORW1, CD 105, CD105 antigen, EGLN, FLJ41744, Osler Rendu Weber syndrome 1, RP11 228B15.2, SN6 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Clone | MJ7/18 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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