Purified Anti-Mouse CD119 Antibody[GR-20] (E-AB-F1115A)
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| Alternate Names | Interferon gamma receptor 1, IFNGR1, INGR1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, Interferon gamma receptor alpha-chain, IFN-gamma-R-alpha, CD119, CDw, IFN-gamma-R, IFN gamma receptor, IFN-gamma receptor, immune interferon receptor, INGR, IFN-γ R, CD119, CD119 antigen, CDw119, Ifgr, IFN gamma receptor 1, IFN-gamma receptor 1, IFN-gammaR, IFN-gamma-R1, IFN-gamma-R-alpha, IFN-γ R1, immune interferon receptor 1, INGR1, Interferon gamma receptor 1, Interferon gamma receptor alpha-chain, interferon-gamma receptor alpha chain, Nktar, Ifngr, Ifngr1, IFN&, gamma-R-R, IFN&, gamma-Ra-a, CDw119 |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
| Immunogen | Recombinant Mouse CD119 protein |
| Abbre | CD119 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3] |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Cell membrane, Membrane
|
| Tissue Specificity |
Expressed in skeleton of lower jaw and 260 other cell types or tissues.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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