Purified Anti-Mouse CD137 Antibody[3H3] (AN010410P)
| Alternate Names | TNFRSF, Cd137, Ila, Ly63, Tnfrsf9, 4-1BB, TNFRSF9 |
| Clone | |
| Verified Samples | Verified Samples in FCM: CTLL-2 |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
| Immunogen | Recombinant Mouse CD137 protein |
| Abbre | CD137 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3], Functional Grade |
| Applications |
FCM
|
| Research Areas | Cell Biology;Immunology;Cancer;Stem Cells |
| Cellular Localization |
Cell membrane, Secreted
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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