Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173], Functional Grade (E-AB-F11140)
![Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Biotin Elab Fluor®488 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Neut Neut- Reported in the literature |
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Applications | FCM, Neut |
| Clonality | Monoclonal |
| Abbre | CD183/CXCR3 |
| Synonyms | C-X-C chemokine receptor type 3, CD183/CXCR3, CXC-R3, CXCR-3, Cxcr3, IP-10 receptor, Interferon-inducible protein 10 receptor |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Research Areas | Immunology, Innate Immunity |
| Clone | CXCR3-173 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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