Purified Anti-Mouse CD45.1 Antibody[A20] (E-AB-F1184A)
![Purified Anti-Mouse CD45.1 Antibody[A20] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Alternate Names | B220, CD45, CD45 antigen, CD45R, CD45R0, LCA, L-CA, LY5, protein tyrosine phosphatase, receptor type, Receptor-type tyrosine-protein phosphatase C, T200, Ly-5, Ptprc, c polypeptide, CD 45, GP180, homolog of, Leukocyte common antigen, loc, Lyt-4, OTTHUMP00000033813, OTTHUMP00000033816, OTTHUMP00000033817, OTTHUMP00000038574, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, receptor type C, T200 glycoprotein, T200 leukocyte common antigen |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD45.1 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
| Immunogen | Recombinant Mouse CD45.1 protein |
| Abbre | CD45.1 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse (A.SW) IgG2a, κ |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Elab Fluor®700
Elab Fluor®Violet 450
FITC
PE
Unconjugated
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