Purified Anti-Mouse FOXP3 Antibody[MF-14] (AN009460P)
![Purified Anti-Mouse FOXP3 Antibody[MF-14] - 1](http://file.elabscience.com/assets/images/loading.png)
Add to cart
For research use only.
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Rat IgG2b, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse Foxp3 protein |
| Abbre | FOXP3 |
| Synonyms | AIID, DIETER, Forkhead box P3, FOXP3delta7, Immune dysregulation polyendocrinopathy enteropathy X linked, Immunodeficiency polyendocrinopathy enteropathy X linked, MGC141961, MGC141963, OTTHUMP00000025832, OTTHUMP00000025833, OTTHUMP00000226737, PIDX, Scurfin, XPID, Forkhead box protein P, FOXP, Forkhead box protein P3, IPEX, JM2, Foxp3 |
| Swissprot | |
| Cellular Localization | Nucleus, Cytoplasm |
| Tissue Specificity | High level of expression in thymus and spleen. |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Clone No. | MF-14 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| E-AB-F1351A | Purified Anti-Mouse Foxp3 Antibody[FJK-16s] | FJK-16s |
-
IF：{{item.impact}}
Journal：{{item.journal}} ({{item.year}})
DOI：{{item.doi}}Reactivity：{{item.species}}
Sample Type：{{item.sample_type}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
