Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody[RB6-8C5], Functional Grade (E-AB-F11200)
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For research use only.
| Verified Samples | Verified Samples in FCM: C57BL/6 Mouse bone marrow cells |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Depletion Depletion - Reported in the literature |
| Isotype | Rat IgG2b, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM, Depletion |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse Gr-1 protein |
| Abbre | Ly-6G/Ly-6C (Gr-1) |
| Synonyms | Gr-1, Gr1, Ly-6G/Ly-6C, Ly6G/Ly6C |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology, Innate Immunity |
| Clone | RB6-8C5 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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