Purified Anti-Mouse Podoplanin Antibody[8.1.1], Functional Grade (AN009680)
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For research use only.
| Alternate Names | Glycoprotein, RANDAM, Aggrus, Glycoprotein 38, OTS-8, PA2.26 antigen, Podoplanin, RANDAM-2, T1a, T1alpha, T1-alpha, Gp38, Ots8, Pdpn |
| Clone | |
| Verified Samples | Verified Samples in FCM: C2C12 cells |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Block Reported in the literaturee |
| Background | The mucin-type glycoprotein podoplanin is thought to be involved in the development of the lymphatic vascular system. Podoplanin is named after its expression in the kidney glomerular epithelial cells (podocytes). It has a potential role in tumor progression. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Mouse Podoplanin protein |
| Abbre | Podoplanin |
| Swissprot | |
| Host | Syrian hamster |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Syrian Hamster IgG2, λ1 |
| Applications |
FCM;Block
|
| Cellular Localization |
Cell junction, Cell membrane, Cell projection, Membrane
|
| Tissue Specificity |
Detected at high levels in lung and brain, at lower levels in kidney, stomach, liver, spleen and esophagus, and not detected in skin and small intestine.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Pengchao Zhang, et al. JCI Insight. 2025 Feb 4;10(6):e186456. |
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