Purified Anti-Mouse/Rat CD61 Antibody[2C9.G2] (AN009470P)
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For research use only.
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse bone marrow |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Armenian Hamster IgG1, κ |
| Host | Armenian Hamster |
| Reactivity | Mouse, Rat |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse CD61 protein |
| Abbre | CD61 |
| Synonyms | BDPLT2, CD61, GP3A, integrin αⅡbβ3, ITG-B3, Platelet Membrane Glycoprotein IIIa, ITGB, Itgb3, gpIIIa, &, beta-3 integrin-n |
| Swissprot | |
| Cellular Localization | Cell membrane |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Clone No. | 2C9.G2 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1). |
| Cat.No. | Product Name | Clone No. |
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