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For research use only.

Verified Samples Verified Samples in WB: Mouse intestinum
Verified Samples in IHC: Human breast cancer, Human brain
Dilution WB 1:200-1:1000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PUS10
Abbre PUS10
Synonyms CCDC139,  Coiled coil domain containing 139,  Coiled coil domain containing protein 139,  Coiled-coil domain-containing protein 139,  DOBI,  FLJ32312,  MGC126729,  PUS10,  Pseudouridine synthase 10,  Pseudouridylate synthase 10,  Psi55 synthase,  Putative tRNA pseudourid,  pus10
Swissprot
Calculated MW 60 kDa
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Metabolism
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.
Other Clones

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Unconjugated

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