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For research use only.

Verified Samples Verified Samples in WB: 231, PC-3
Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution WB 1:500-1:2000,  IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human PYGL
Abbre PYGL
Synonyms GSD6,  Glycogen phosphorylase,  Glycogen phosphorylase L,  Glycogen phosphorylase liver,  Glycogen phosphorylase liver form,  Hers disease,  OTTHUMP00000233649,  OTTHUMP00000233651,  PYGL,  Phosphorylase glycogen liver,  Pygl,  glycogen storage disease type VI,  liver form
Swissprot
Calculated MW 97 kDa
Cellular Localization Cytosol, Extracellular region or secreted, extracellular exosome, extracellular region, Other locations: cytoplasm, ficolin-1-rich granule lumen, secretory granule lumen.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores.This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15.Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls.Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
Other Clones

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Unconjugated

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