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For research use only.

Verified Samples Verified Samples in WB: K562
Verified Samples in IHC: Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human RAB27A
Abbre RAB27A
Synonyms GS2,  GTP-binding protein Ram,  HsT18676,  MGC117246,  Mutant Ras related protein Rab-27A,  RAB-27A,  RAB27,  RAB27A,  RAB27A member RAS oncogene family,  RAM,  RB27A,  Rab-27,  Ras-related protein Rab-27A,  Ras-related protein Rab27A
Swissprot
Calculated MW 25 kDa
Cellular Localization Membrane. Melanosome. Late endosome. Lysosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Other Clones

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Unconjugated

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