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For research use only.

Verified Samples Verified Samples in WB: 231
Verified Samples in IHC: Human breast cancer, Human gastric cancer
Dilution WB 1:500-1:2000,  IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human AGER
Abbre AGER
Synonyms Advanced glycosylation end product-specific receptor,  Ager,  MGC2235,  RAGE,  Receptor for advanced glycosylation end products
Swissprot
Calculated MW 43 kDa
Cellular Localization Secreted and Cell membrane.
Concentration 1.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene.
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Unconjugated

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