RAP1A Polyclonal Antibody (E-AB-13927)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human lung cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human RAP1A |
| Abbre | RAP1A |
| Synonyms | C21KG, G-22K, GTP-binding protein smg p21A, KREV1, RAP1A, Ras-related protein 1A, Ras-related protein Krev-1, Ras-related protein Rap-1A, SMGP21, member of RAS oncogene family |
| Swissprot | |
| Cellular Localization | Cell membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The product of this gene belongs to the family of RAS-related proteins.These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common.The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins.The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.Two transcript variants encoding the same protein have been identified for this gene. |
Other Clones
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Other Formats
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Unconjugated
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