Rat gp130 Antibody Pair Set (E-KAB-0382)
For research use only.
| Background |
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
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| Synonyms |
Il6st,
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| Swissprot | |
| Reactivity |
Rat
|
| Specificity |
Detects Rat gp130 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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