Rat PAI1 Antibody Pair Set (E-KAB-0644)
For research use only.
| Background |
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator ( PLAT ) and urokinase-type plasminogen activator ( PLAU ) . As PLAT inhibitor , it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor , it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration , independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells , and regulates odontoblast differentiation and dentin formation during odontogenesis.
|
| Synonyms |
Endothelial Plasminogen Activator Inhibitor, PAI, PAI-1, PLANH1, SERPINE1
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| Swissprot | |
| Reactivity |
Rat
|
| Specificity |
Detects Rat PAI1 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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