Recombinant 4E-BP1/EIF4EBP1 Monoclonal Antibody (AN300047P)
For research use only.
| Verified Samples | Verified Samples in IF: Hela |
| Dilution | ICC/IF 1:20-1:100, |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | ICC/IF |
| Clonality | Rabbit Monoclonal |
| Immunogen | Recombinant Human 4E-BP1 / EIF4EBP1 protein |
| Abbre | EIF4EBP1 |
| Synonyms | 4EBP, eIF4E binding protein, eukaryotic translation initiation factor 4E-binding protein, 4E-BP, EIF4EBP, EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E-binding protein 1, BP 1, eIF4E binding protein 1, eIF4E-binding protein 1, PHASI, Phosphorylated heat- and acid-stable protein regulated by insulin 1, 4EBP1, 4E-BP1, BP-1, eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cytosol. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Epigenetics and Nuclear Signaling, Metabolism |
| Clone No. | 2C3 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
Other Clones
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Unconjugated
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