Recombinant ABCB11/BSEP Monoclonal Antibody (AN301450L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human liver |
| Dilution | IHC 1:200-1:1000 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human ABCB11/BSEP fragment |
| Abbre | ABCB11/BSEP |
| Synonyms | PGY, ABC, ABCB, BRIC, ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Signal Transduction, Cancer, Metabolism |
| Clone No. | A145 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates to hepatic bile acids homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts. Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion. |
Other Clones
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Other Formats
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Unconjugated
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