Recombinant ADAM15/MDC15 Monoclonal Antibody (AN300194P)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human lymphonode of endothelial cells, Human heart blood vessel Verified Samples in IF: Hela Verified Samples in FCM: MCF-7 |
| Dilution | IHC-P 1:1000-1:4000, ICC/IF 1:20-1:100, FCM 1:25-1:100, |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P, FCM, ICC/IF |
| Clonality | Recombinant;Monoclonal |
| Immunogen | Recombinant Human ADAM15 protein |
| Abbre | ADAM15 |
| Synonyms | MDC, ADAM, ADAM15, MDC15 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Signal Transduction, Cancer, Cell Biology |
| Clone No. | 7C7 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 0. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Other Clones
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Other Formats
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Unconjugated
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