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Recombinant Apolipoprotein H/APOH Monoclonal Antibody (AN300392P)

Recombinant Apolipoprotein H/APOH Monoclonal Antibody - 1
  • Recombinant Apolipoprotein H/APOH Monoclonal Antibody - 1
  • Recombinant Apolipoprotein H/APOH Monoclonal Antibody - 2
All Size Price Qty
100μL $ 320.00
- +
50μL $ 211.00
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For research use only.

Verified Samples Verified Samples in IHC:paraffin-embedded human liver
Dilution WB 1:1000,  IHC-P 1:200-1:500,  ICC/IF 1:100,  FC 1:200-1:500,  IP 1:20-1:50
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P
Clonality Monoclonal
Immunogen Recombinant Human APOH protein
Abbre APOH
Synonyms B2G,  B2GP,  Beta-2-Glycoprotein,  APOH B2G,  APOH,  B2G1,  B2GP1,  BG,  Activated Protein C-Binding Protein,  Anticardiolipin Cofactor,  APC inhibitor,  Apo-H,  Apolipoprotein H,  B2GPIBeta(2)GPI,  Beta-2-Glycoprotein 1,  Beta-2-Glycoprotein I,  APOH B2G1,  Activated protein C binding protein,  apolipoprotein H (beta-2-glycoprotein I),  B2GPI,  Beta 2 glycoprotein I,  Beta 2 glycoprotein I precursor,  Beta(2) GPI,  Beta(2)GPI,  beta-2,  Glycoprotein 1,  Glycoprotein I,  OTTMUSP00000003033
Swissprot
Calculated MW 38 kDa
Tissue Specificity Expressed by the liver and secreted in plasma.
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Affinity Purification
Research Areas Cardiovascular,  Signal Transduction,  Metabolism
Clone B318
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019]
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