Recombinant c-erbB-3/HER-3 Monoclonal Antibody (AN301516L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human colon, Human breast cancer |
| Dilution | IHC 1:100-1:1000 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human c-erbB-3/HER-3 fragment |
| Abbre | c-erbB-3/HER-3 |
| Synonyms | HER, LCCS, Proto-oncogene-like protein c-ErbB, Tyrosine kinase-type cell surface receptor HER, MDA-BF, p180-ErbB, p45-sErbB, p85-sErbB, ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, EEBB3 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Plasma membrane |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Signal Transduction, Cancer |
| Clone No. | A215 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5). Involved in the regulation of myeloid cell differentiation. |
Other Clones
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Unconjugated
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