Recombinant CD278/ICOS Monoclonal Antibody (AN301473L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human cervical cancer, Human tonsil |
| Dilution | IHC 1:200-1:1000 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human CD278/ICOS fragment |
| Abbre | CD278/ICOS |
| Synonyms | CVID, ICOS, AILIM, CD278, CVID1, activation-inducible lymphocyte immunomediatory molecule, Inducible T-cell costimulator |
| Swissprot | |
| Cellular Localization | Plasma membrane, Cytoplasm |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Immunology |
| Clone No. | A168 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. |
Other Clones
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Other Formats
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Unconjugated
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