Recombinant CD35 Monoclonal Antibody (AN301476L)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon, Human kidney Verified Samples in IF: PBMCs |
| Dilution | IHC 1:200-1:1000, IF 1:50 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | IHC, IF |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human CD35 fragment |
| Abbre | CD35 |
| Synonyms | Complement receptor type, CR1, C3BR, CD35, Complement receptor type 1, C3b/C4b receptor, C3b/C4b-R |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Immunology, Stem Cells |
| Clone No. | A171 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CD35, also known as complement receptor 1 (CR1), is a 220-300 kDa N-glycosylated member of the RCA (regulators of complement activation) family of proteins. CD35 binds and internalizes particles and immune complexes that are opsonized with MBL or complement components C3b, C3i, C4b, or C1q. CD35 additionally protects the cell from complement-mediated lysis by serving as a cofactor for Factor I and inhibiting the C3 and C5 convertases. The extracellular domain (ECD) of human CD35 contains 30 tandem SCR/SUSHI repeats. |
Other Clones
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Other Formats
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Unconjugated
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