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100μL $ 380.00
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For research use only.

Verified Samples Verified Samples in IHC: Human placenta
Verified Samples in IF: HepG2
Dilution IHC-P 1:100-1:500,  ICC/IF 1:20-1:100,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P,  ICC/IF
Clonality Rabbit Monoclonal
Immunogen Recombinant Human CD46 protein
Abbre CD46
Synonyms MIC,  AHUS,  TRA2.,  AHUS2,  MCP,  MIC10,  TLX,  TRA2.10,  CD46,  CD46 molecule,  Membrane Cofactor Protein,  Trophoblast Leukocyte Common Antigen
Swissprot
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Immunology
Clone No. 10A2
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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Unconjugated

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