Recombinant CEACAM1/CD66a Monoclonal Antibody (AN300208P)

Name: Recombinant CEACAM1/CD66a Monoclonal Antibody
Brand: Elabscience
SKU: AN300208P
Price: 150.0 USD
Availability: InStock

Copy the product info.

Citations ({{ citationsPage.numTotal }}) Manual MSDS

Resources

Recombinant CEACAM1/CD66a Monoclonal Antibody - 1

All	Size	Price	Qty
	100μL	$ 380.00	- +
	20μL	$ 150.00	- +

Bulk request

Add to cart

For research use only. Order now, ship in 3 days

Verified Samples	Verified Samples in WB:A549
Dilution	WB: 1:2000-1:20000；IHC-P: 1:50-1:100；IP: 1:10-1:100
Isotype	IgG
Host	Rabbit
Reactivity	Human
Applications	WB, IHC-P, IP
Clonality	Recombinant;Monoclonal
Immunogen	Recombinant Human CEACAM1 / CD66a protein
Abbre	CEACAM1
Synonyms	Biliary Glycoprotein, Carcinoembryonic Antigen-Related Cell Adhesion Molecule, CEACAM, CEACAM1, BGP, BGP1, BGPI, BGP-1, Biliary Glycoprotein 1, Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1, CD66a, NCA-160, Antigen CD66, BGP 1, Biliary glycoprotein adhesion molecule, Carcinoembryonic antigen related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), CD66a antigen, CEAM1, meconium antigen 100
Swissprot	P13688
Calculated MW	58 kDa
Observed MW	120-160 kDa The actual band is not consistent with the expectation. Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane.
Cellular Localization	Cell membrane, Secreted.
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Tags and Cell Markers, Immunology, Cancer, Microbiology
Clone	B126
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]