Recombinant Claudin 18.2 Monoclonal Antibody (AN301831L)
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For research use only.
| Verified Samples | Verified Samples in IHC: Human stomach, Human gastric cancer, Mouse stomach, Rat stomach |
| Dilution | IHC 1∶200-1∶1000 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, Rat, Mouse |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human Claudin 18.2 fragment |
| Abbre | Claudin 18.2 |
| Synonyms | UNQ, PRO, CLDN, SFTA, Claudin, Claudin-, CLDN18, SFTA5, SFTPJ, Claudin-18, Claudin-18.2, UNQ778, PRO1572, SPJ |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Signal Transduction |
| Clone No. | A543 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions. Claudins exhibit specific patterns of expression in different tissues. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm. |
Other Clones
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Other Formats
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Unconjugated
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