Recombinant FBXW7 Monoclonal Antibody (AN301521L)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human breast cancer, Human colon Verified Samples in IF: HeLa, MCF7 |
| Dilution | IHC 1:100-1:1000, IF 1:50 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | IHC, IF |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human FBXW7 fragment |
| Abbre | FBXW7 |
| Synonyms | FBX, CDC, FBXO, hCdc, FBW, SEL, FBXW7, AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4, Archipelago, Archipelago homolog, DKFZp686F23254, Drosophila, Drosophila), E3 ubiquitin protein ligase, F box and WD 40 domain protein 7, F box and WD 40 domain protein 7 (archipelago homolog, F box and WD repeat domain containing 7, F box protein FBW7, F box protein FBX30, F box protein SEL 10, F box protein SEL10, F-box and WD repeat domain containing 7, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FLJ16457, homolog of, Homolog of C elegans sel 10, Homolog of C.elegans sel10, S.cerevisiae, SEL 10 |
| Swissprot | |
| Cellular Localization | Nucleus |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Cell Biology, Cancer |
| Clone No. | A220 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. |
Other Clones
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Other Formats
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Unconjugated
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