Recombinant Galectin-3 Monoclonal Antibody (AN301191L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human colon carcinoma |
| Dilution | IHC 1:2000-1:6000 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human Galectin-3 protein |
| Abbre | Galectin-3 |
| Synonyms | MAC, Galactose-specific lectin, Galactoside-Binding Soluble, Galectin, Lectin L, GAL, CBP, LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, Galactoside-Binding Soluble 3, Lectin, Galectin-3, Gal-3, L-31, 35 kDa lectin, CBP 35, Galactose-specific lectin 3, IgE-binding protein, Laminin-binding protein, Lectin L-29, Mac-2 antigen, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, galactose binding, galactoside binding soluble 3, Galactoside-binding protein, galectin 3, Galectin 3 internal gene, Galectin3, GBP, IgE binding protein, included, L 31, L 34, L-34 galactoside-binding lectin, Lectin, Galactoside-Binding Soluble 3, LEG3, MAC 2 antigen, Mac-2, Macrophage galactose-specific lectin, MGC105387, P35, soluble 3, Galectin-3 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Nucleus. Secreted, Secreted by a non-classical secretory pathway and associates with the cell surface. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). |
| Tissue Specificity | Colonic epithelium, activated macrophages, fetal membranes. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Neuroscience, Cell Biology |
| Clone No. | B950 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants. |
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Unconjugated
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