Recombinant Green monkey Calcitonin/CT protein (His Tag) (PDMC100004)
For research use only.
| Synonyms | CALCA, Calcitonin |
| Species | Green monkey |
| Expression Host | HEK293 Cells |
| Sequence | Ala26-Asn140 |
| Accession | A0A0D9QXH0 |
| Calculated Molecular Weight | 12.5 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Form | Lyophilized powder |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | Calcitonin(CT) is a protein hormones consist of 115aa with a disulfide bond. Calcitonin (CT) is most effectively produced by the parafollicular cells of the thyroid gland. It acts through the calcitonin receptor (CTR), a seven-transmembrane class II G-protein-coupled receptor linked to multiple signal transduction pathways with its main secretagogues being calcium and gastrin. Calcitonin regulates blood calcium levels and possesses certain clinically useful anti-fracture properties. |
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