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Recombinant Human C1QBP Protein (aa 74-282, His Tag) (PKSH033350)

All Size Price Qty
50μg $ 198.00
10μg $ 88.00
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For research use only.

Synonyms ASF/SF2-Associated Protein p32, C1QBP, C1qBP, Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial, GC1QBP, Glycoprotein gC1qBP, HABP1, Hyaluronan-Binding Protein 1, Mitochondrial Matrix Protein p32, SF2P32, gC1q-R Protein, gC1qR, p33
Species Human
Expression Host E.coli
Sequence Leu74-Gln282
Accession Q07021
Calculated Molecular Weight 24.9 kDa
Observed Molecular Weight 34 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 1mM DTT, pH 7.5.
Reconstitution Not Applicable
Background Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
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