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Recombinant Human Carbonic Anhydrase 8/CA8 Protein (His Tag) (PKSH031586)

All Size Price Qty
100μg $ 580.00
1mg $ 3560.00
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For research use only.

Synonyms CA-VIII, CA8, CALS, CAMRQ3, CARP, Carbonic Anhydrase VIII, Carbonic Anhydrase-Related Protein, MGC120502, MGC99509
Species Human
Expression Host E.coli
Sequence Met 1-Gln 290
Accession NP_004047.3
Calculated Molecular Weight 33.8 kDa
Observed Molecular Weight 37 kDa
Tag C-His
Bio-activity Measured by its esterase activity. The specific activity is > 100 pmoles/min/μg.
Purity > 94 % as determined by reducing SDS-PAGE.
Endotoxin Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, 15% glycerol, pH 7.5
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.
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