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Recombinant Human CDKL2 Protein (His Tag) (PKSH030371)

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50μg $ 438.00
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For research use only.

Synonyms KKIAMRE, P56
Species Human
Expression Host Baculovirus-Insect Cells
Sequence Met 1-His 493
Accession Q92772
Calculated Molecular Weight 58.3 kDa
Observed Molecular Weight 63 kDa
Tag N-His
Bio-activity Not validated for activity
Purity > 80 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol
Reconstitution Not Applicable
Background Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus, amygdala, and dorsal thalamus. The high expression in these brain regions suggests that Cdkl2 may have functions in congnition and emotion processes. Cdkl2 accumulates primarily in the cytoplasm, with lower levels in the nucleus.
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