Recombinant Human COL9A1 Protein (Fc Tag) (PKSH030873)

For research use only.
Synonyms | Collagen alpha-1(IX) chain, DJ149L1.1.2, DJ149L1.1.2 , EDM6, MED, STL4 |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Met 1-Pro328 |
Accession | P20849-3 |
Calculated Molecular Weight | 59.2 kDa |
Observed Molecular Weight | 62-72 kDa |
Tag | C-mFc |
Bio-activity | Not validated for activity |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | Ubiquinone biosynthesis protein COQ7 homolog; also known as Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog and COQ7; is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix; where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical; and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site; a phosphorylation site for protein kinase C and another for casein kinase II; and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator. |
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