Recombinant Human E-Selectin/SELE Protein (His Tag) (PKSH032403)

For research use only.
Synonyms | CD62 antigen-like family member E, CD62E and ELAM1, E-selectin (SELE), ELAM, ESEL, Endothelial leukocyte adhesion molecule 1, LECAM2, Leukocyte-endothelial cell adhesion molecule 2 |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Trp22-Pro556 |
Accession | P16581 |
Calculated Molecular Weight | 58.6 kDa |
Observed Molecular Weight | 104 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | SELE is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. SELE functions as a cell-surface glycoprotein and has a role in immunoadhesion. In addition, SELE may also have a role in capillary morphogenesis. |
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