Recombinant Human FKBP2 Protein (His Tag) (PKSH032875)

For research use only.
Synonyms | FK506-binding protein 2, Immunophilin FKBP13, Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), Rotamase, also named 13 kDa FK506-binding protein |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Ala22-Leu142 |
Accession | P26885 |
Calculated Molecular Weight | 14.3 kDa |
Observed Molecular Weight | 17 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mm NaCl, pH 7.5. |
Reconstitution | Not Applicable |
Background | Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds. |
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