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Recombinant Human FKBP4 Protein (His Tag) (PKSH032877)

All Size Price Qty
50μg $ 268.00
10μg $ 198.00
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For research use only.

Synonyms 51kDa FK506-binding protein, 59kDa immunophilin, FK506-binding protein 4, FKBP4, FKBP59, HSP-binding immunophilin, Peptidyl-prolyl cis-trans isomerase FKBP4, Rotamase, immunophilin FKBP52
Species Human
Expression Host E.coli
Sequence Met 1-Ala459
Accession Q02790
Calculated Molecular Weight 52.8 kDa
Observed Molecular Weight 50-60 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
Reconstitution Not Applicable
Background FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
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