Recombinant Human Galectin-1/LGALS1 Protein (His Tag) (PKSH032471)
For research use only.
| Synonyms | 14 kDa Laminin-Binding Protein, 14 kDa Lectin, Beta-Galactoside-Binding Lectin L-14-I, GAL1, GBP, Gal-1, Galaptin, Galectin-1, HBL, HLBP14, HPL, LGALS1, Lactose-Binding Lectin 1, Lectin Galactoside-Binding Soluble 1, Putative MAPK-Activating Protein PM12, S-Lac Lectin 1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ala2-Asp135 |
| Accession | P09382 |
| Calculated Molecular Weight | 15.5 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | N-His |
| Bio-activity | Measured by its ability to agglutinate human red blood cells.The ED50 for this effect is <2 μg/mL. |
| Purity | > 98 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties. |
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